For model calibration, phosphoproteomic time course data from protein microarrays39 for the receptor phosphorylation as well as for phospho-MEK, phospho-ERK, phospho-AKT, and phospho-S6 across all seven cancer cell lines (H322M, BxPc-3, A431, BT-20, ACHN, ADRr, and IGROV-1) were used. This evidence concerns the gene MAP2K7 and cancer.