CSPG4 and leukemia: Importantly, secondary leukemias from NG2+ and NG2− primografts retained a pro-B phenotype (Supplementary Figure S1A), similar infiltration levels in BM and extramedullary hematopoietic sites (Figure 3b), splenomegaly, high WBC counts (Figure 3c) and skewed differentiation toward the lymphoid compartment in PB (Supplementary Figure S1B).