CSPG4 and acute lymphoblastic leukemia: Interestingly, however, while NG2 does not enrich for L-IC or CNS-IC in iMLLr-B-ALL, its expression is malleable as determined by the ability of both NG2+ and NG2− cell fractions to re-establish in vivo the original leukemia immunophenotype with a continuum of NG2 expression.