MET and colonic neoplasm: MET amplification is less common than overexpression of the protein receptor tyrosine kinase [17], but has been noted primarily in gastrointestinal cancers such as gastric cancer, oesophageal cancer [18] and colon cancer, as well as in endometrial carcinoma, medulloblastoma, non-small cell lung cancer (NSCLC) [19] and gliomas [20].