MET and neoplasm: The three trials defined different IHC cut-off criteria: at least 50% tumour cells with 2+ or 3+ staining was referred to as “MET diagnostic positive” in the ornatuzumab study and “MET-high” in the tivantinib study, whereas the rilotumumab study defined “MET-positive” as at least 25% membrane staining of tumour cells at any intensity.