Furthermore, the p-JNK (p < 0.001) and NFκB (p = 0.005) levels were significantly higher in the HF group compared to the control group, while the teasaponin treatment prevented an increase of p-JNK and NFκB (p < 0.001, p = 0.008) (Fig. 3). Here, MAPK8 is linked to hydrops fetalis.