PITX2 and cholesteryl ester measurement: At the 4q25 (PITX2) locus, previously identified by GWAS, we confirmed the association at rs2634074 with CE stroke (OR = 1.43 for the T allele; 95% CI, 1.13–1.81, p = 0.029), but not at rs2200733 (OR = 1.30 for the T allele; 95% CI, 0.96–1.76; p = 0.60) (Table 1).