Thus, analysis of GEO gene expression dataset of HNSCC (GSE2837) based on MMP10 transcript expression performed showed poor survival in the cancer patients with high MMP10 expression, similar to as observed in breast cancer (GSE2990), lung cancer (GSE31210; 11117), liposarcomas (GSE30929), and colorectal cancer (GSE12945) using PrognoScan [42] and PROGgene [43] (Fig. 4). Here, MMP10 is linked to head and neck squamous cell carcinoma.