KMT2A and leukemia: The downstream effect of MLL1 stabilisation (as observed in Cks1−/− MEFs) has been well documented in MLLr leukaemia [28], [30], [31], [63], [64], in which the normal epigenetic profile and cooperating signalling pathways, governed by MLL1, are hijacked by MLL-FPs [48], [65], [66], [67], [68], [69].