Among 47 allo-HSCT recipients, univariate analysis showed that high levels of serum CRP (≥10.0 mg/dl), low levels of serum albumin (<3.0 g/dl), increased serum creatinine levels (≥1.0 mg/dl), high disease risk, severe sepsis or septic shock, initial source of infection, time to appropriate therapy, non-removal of CVC, and reduced-intensity conditioning regimens were significant risk factors for overall 90-day mortality. The gene discussed is ALB; the disease is Sepsis.