EGFR and malignant colon neoplasm: miR-20b reduced 5-FU resistance for apoptotic induction by inhibiting ADAM9/EGFR pathway in colon cancer cells [19], whereas miRNA-34c-5p inhibited amphiregulin-induced chemoresistance to docetaxel and carboplatin in ovarian cancer cells via the downregulation of AREG-EGFR pathway [20].