EGFR and central nervous system cancer: The SNP 11506105 in EGFR was identified to be associated with an increased risk of glioma, according to allele G association analysis, which is inconsistent with a previous study in a European population, the A allele of rs11506105 had been found to be associated with increased risk of glioma (OR = 1.39, 95%CI: 1.08-1.78, p = 0.012) [16].