Tissue TMA-IHC assay showed a strong correlation between the SPON2 gene and protein expression, SPON2 protein was expressed higher on ADC epithelial cell membranes (Figure 2C1–D1, 2C2–D2) than on normal lung tissues (Figure 2A1–B1, 2A2–B2). This evidence concerns the gene SPON2 and AIDS dementia complex.