Remarkably, low PATZ1 samples shown in Figure 6B and 6C were mostly characterized (11 out of 14) by increased expression of the G-protein coupled receptor CXCR4 (Supplementary Table 5), which has been shown to induce and assist in the maintenance of a mesenchymal expression profile in GBM cells [31] and is overexpressed in CD133+ cells from human GBMs resistant to chemotherapy [32]. This evidence concerns the gene PROM1 and glioblastoma.