PATZ1 and central nervous system cancer: Consistent with the enrichment of PATZ1 in the proneural subtype, we showed in our local cohort of gliomas, that patients with low PATZ1 score (0/+) had a worse overall survival (OS) than patients with high PATZ1 score (++/+++) (HR = 2.525, 95% CI = 1.208-5.280, p = 0.0138) (Figure 6A).