The combined status of PD-L1 expression and the T-I was an independent and significant prognostic factor for OS at each 1%, 5% and 10% cut-off value in patients with MSI-H GC (p = 0.030 for 1% cut-off value; p = 0.024 for 5% cut-off value; p = 0.019 for 10% cut-off value) (Table 3), and notably, the patients with PD-L1 (+)/T-IHigh tumors showed a significantly better clinical outcome than patients with PD-L1 (+)/T-ILow tumors (p = 0.008 for 1% cut-off value; p = 0.007 for 5% cut-off value; p = 0.042 for 10% cut-off value) (Table 3). The gene discussed is CD274; the disease is gastric cancer.