The expression of some genes, which are associated with cell cycle checkpoint and cell cycle arrest, were up-regulated at 8 hours post infection, including CDK2, RBBP8, CDK1, KNTC1, CDC25A, BRCA1, and BRCA2. It is well known that several cyclin-dependent kinases (CDKs) can be activated by CDC25A/B/C in the cell cycle. The gene discussed is RBBP8; the disease is infection.