In this study, we used immunohistochemistry (IHC) to assess the prognostic role of PD-L1 in the OS of patients with surgically resected NSCLC and the association between PD-L1 expression and clinicopathologic characteristics, including histologic type, sex, age, and pathologic tumor-node-metastasis (TNM) stage. The gene discussed is CD274; the disease is neoplasm.