Therefore, in this study we assessed the effects of the nine SNPs in the CD20, FCGR2A, NAD(P)H, ABCC2, ABCG2 and CYP3A5 gene on survival in a cohort of 189 Chinese DLBCL patients treated with R-CHOP to define specific subgroups more likely to benefit from therapy. This evidence concerns the gene CYP3A5 and diffuse large B-cell lymphoma.