The results showed that PTIP expression was positively correlated with liver cirrhosis (P=0.008), tumor number (P=0.029), vascular invasion (P= 0.003), capsular formation (P<0.001), Edmondson-Steiner grade (P=0.010), BCLC Stage (P=0.018) (Table 1). This evidence concerns the gene PAXIP1 and cirrhosis of liver.