In our previous study on brain metastases [17] and in the present study, a significant [18F] FDOPA uptake (defined by a ratio SUVmax T/S >0.75) in tumours was correlated with a LAT1 score higher than 100, suggesting that, as expected, LAT1 expression may play an important role in [18F] FDOPA uptake and that a minimal LAT1 expression is required for [18F] FDOPA uptake. The gene discussed is SLC7A5; the disease is neoplasm.