GSTM1 and heart failure: We found that V ̇O2 peak, maximal cardiac output (CI max) and cerebral oxygenation and perfusion (ΔO2 Hb, ΔtHb) during exercise and, to a lesser degree during recovery, were related to resting cognitive function (short term and working memory, psychomotor speed, cognitive inhibition and flexibility and long term verbal memory) in agreement with previous studies in healthy subjects, heart failure and transplanted patients [10, 11, 45].