NFKB1 and schizophrenia: Moreover, as NF-κB has been linked to neuroinflammatory responses in relation to neurodegeneration [56] and schizophrenia [57], we suggest that dysbindin-1A interaction with the NF-κB signaling cascade is responsible for localized neuroinflammation in higher areas of the brain involved in the behavioral and clinical symptoms of schizophrenia.