In fact, alterations in AMPA receptor binding or the levels of mRNA of the GluR1 or GluR2 AMPA receptor subunits following withdrawal of diazepam were discovered in brain areas implicated in anxiety (i.e., hippocampus, amygdala, thalamus, or limbic-associated cortex) (Allison and Pratt 2006). Here, GRIA1 is linked to Anxiety.