Importantly, antigen adsorbed to CAF09 liposomes efficiently induces cross-priming by dendritic cells (DCs), and the induction of antigen-specific CD8+ T cells has been documented with several different antigens on proteins or peptides.25 In addition, CD8+ T cells elicited by CAF09 in combination with the E7 antigen from HPV16 confer complete protection in a prophylactic skin tumor model and enhanced protection as measured by reduced tumor growth for all mice in a therapeutic tumor model.25 The gene discussed is CD8A; the disease is skin neoplasm.