SOSTDC1 and diabetes mellitus: We have recently reported novel atherosclerosis-related antibody markers, such as antibodies against RPA2 for stroke [10], antibodies against SOSTDC1 and TUBB2C for CI and DM [11,12], and antibodies against ATP2B4 and BMP-1 for atherosclerosis-related diseases, such as CI, CAD, DM and chronic kidney disease [13].