Recent studies have shown that elevated levels of highly sensitive cardiac troponin I (hs-cTnI) and T (hs-cTnT) as biomarkers of subclinical myocardial injury may provide to be clinically useful prognostic information, concerning both the future risk of HF's manifestation in asymptomatic subjects and the risk of fatal events and primary/re-admissions in the hospital in those with already established symptomatic acute, acutely decompensated and chronic stable HF related to ischaemic and non-ischaemic causes [24, , –27]. The gene discussed is TNNT2; the disease is hydrops fetalis.