In another study, Neeland et al. [30] reported that identifying a malignant sub-phenotype of LVH was the better predictive surrogate marker than a limited elevated level of hs-cTnT, and even increased NT-proBNP among asymptomatic individuals with a high risk of progression to HF and CV death in the general population. This evidence concerns the gene TNNT2 and hydrops fetalis.