Infected C57BL/6 mice treated with anti-IL-10R displayed significantly higher plasma levels of IFN-γ than the control group, which was associated with an early mortality (died on 7–10 days post infection); the early death of the infected mice could be prevented by neutralization of IFN-γ, demonstrating that IFN-γ is the killer (12). Here, IFNG is linked to infection.