When the cut-off value of anti-PLA2R-IgG concentration was set at 0.91 mg/L, patients had a 84.06% positive rate of IMN, 41.82% IgA nephropathy, 50% lupus nephritis, 58.33% minimal change disease, and 40% other renal diseases. The gene discussed is PLA2R1; the disease is lupus nephritis.