Although elevated low-density lipoprotein cholesterol (LDL-C) represents a major contributor for CHD [1], it is frequently observed that plasma triglyceride (TG) levels still remain high in some CHD patients despite their satisfactory reduction of LDL-C by statins (also known as HMG-CoA reductase inhibitors), a widely-prescribed class of lipid-lowering medications that reduce atherosclerotic cardiovascular risk primarily via LDL-C reduction [1]. Here, HMGCR is linked to coronary artery disorder.