The new discovery of ACT-PLA activity opens a new window not only to continue investigating the mechanistic and molecular details of AC transport across cell membranes, but also to explore how this ACT-PLA activity can be regulated and, thus, opens new possibilities for the therapeutic control of whooping cough, an infectious disease that is the fifth largest cause of vaccine-preventable death in infants. This evidence concerns the gene ASAH1 and pertussis.