GSN and Nager acrofacial dysostosis: The other proteins identified in the female panel (actin α-cardiac muscle 1, isoform 1 of gelsolin, kallistatin, paraoxonase 1, pigment epithelium-derived factor, protein Z-dependent protease inhibitor) are associated with the protease activity, the antioxidant effects, as well as with the cytoskeletal composition, which is a unique feature when compared with the whole AFD group [57].