In particular, PCT values between ≥0.5 and 2.0 ng/mL are suggestive of moderate risk for progression to systemic inflammation, between 2.0 and 10 ng/mL are suggestive for high risk for progression to systemic inflammation, whereas values ≥10 ng/mL are associated with a high probability of developing severe sepsis and septic shock [1]. Here, CALCA is linked to Sepsis.