Recent studies have revealed a genetic contribution of the HLA-B*27:05 allele in predicting ATD-induced agranulocytosis in White European populations23, whereas HLA-B*38:02 and HLA-DRB1*08:03 are the genetic predictors of ATD-induced agranulocytosis in Chinese patients from Hong Kong22 and Taiwan21. This evidence concerns the gene HLA-B and Absence of circulating granulocytes.