TENT5C and Miyoshi myopathy: Furthermore, the presented data strongly indicate that FAM46C is a B-cell lineage-specific growth suppressor as silencing of FAM46C in MM cells that express the wild-type protein enhances cell division, whereas introduction of wild-type FAM46C into MM that express the protein with mutations leads to growth arrest; also, primary B cells isolated from FAM46C KO animals proliferate faster.