Further, the highly organized CD45R+ B cell aggregates mirror human renal inflammation (36) and lupus nephritis (37), with features of tertiary lymphoid organs previously identified in kidney allografts (38), aged atherosclerosis-prone hyperlipidemic ApoE–/– mice (39), and in aged, but not young, mice 45 days after AKI (40). This evidence concerns the gene PTPRC and acute kidney injury.