With the hepatic transaminases (Figure 2c,d), there was a trend of increased ALT caused by maternal obesity (+0.74-fold, p < 0.1), which may be explained by the elevated concentrations of this transaminase in the Ob_KO with respect to the C_wt group (+1.68-fold, p < 0.1). The gene discussed is GPT; the disease is obesity due to melanocortin 4 receptor deficiency.