The significant upregulation of TFF3 RNA expression in PC was confirmed in two additional patient sample sets, including 126 PC + 29 AN and 36 PC + 19 AN [40,41] tissue samples profiled on microarrays (p < 0.001 and p = 0.019; Figure S4A,B), and also had similar AUCs (0.727 and 0.716 by ROC curve analysis). The gene discussed is TFF3; the disease is pachyonychia congenita.