Although TFF3 RNA expression did not remain significant after correction for Gleason score and pT-stage (p = 0.177; Table S1) in this patient cohort with relatively limited follow-up and few PSA recurrences (Table 1), Kaplan–Meier analyses showed that PC patients with low TFF3 expression had significantly increased risk of PSA recurrence (Figure 3A, p = 0.039, log-rank test). This evidence concerns the gene TFF3 and pachyonychia congenita.