For example, in a recent paper by White and colleagues [87], which aimed to define genetic events that occur in the months after the expression of oncogenic BRAF, genomic DNA was isolated from ZMEL1—a cell line previously generated from a melanoma derived from a 6 months old Tg(mitfa:BRAFV600E;p53zdf1/zdf1;mitfa−/−) fish [68,88]—and compared to DNA derived from normal zebrafish muscle tissue. The gene discussed is BRAF; the disease is melanoma.