MMP9 and Familial prostate cancer: For instance, 6-gingerol was found to have a role in the suppression of the hyper-proliferation, transformation, and inflammatory routes that take part in numerous steps of carcinogenesis, angiogenesis and metastasis; in addition, it acts in the initiation of apoptosis in the prostate cancer cell line via inhibition of cell invasion reduction of matrix metalloproteinase-9 expression.