The analysis of NMP22, BLCA, and NMBL proteins performed according to tumor stage (T) and grade (G) [Ta (n = 43), T1 (n = 31), T2 (n = 10), and TIS (n = 7); G1 (n = 40), G2 (n = 41), and G3 (n = 3)] showed no differences between subgroups T and G in NMP22 level; however, there were statistically significant differences in BLCA-4 concentration between Ta and T1 (p = 0.0115), Ta and T2 (p = 0.0288), and Ta and TIS (p = 0.0255) (Figure 1(a)). The gene discussed is NUMA1; the disease is neoplasm.