CXCL12 and breast cancer: The generalized computational modeling of Rene’ Thomas (Thomas, 1973; Thomas, 2002; Thomas & Kaufman, 2001a; Thomas & Kaufman, 2001b; Thomas & Kaufman, 2002; Thomas, Thieffry & Kaufman, 1995) provide a dynamical insights to study the molecular mechanism of involvement of CXCR4 and CXCL12 in the metastasis of BC.