Due to a known metastatic function of chemokine, CXCL12 variant is considered as a risk factor and has been previously reported in association with multiple cancers including myeloma (Luker & Luker, 2006; Pemberton et al., 2006), colorectal (Hidalgo-Pascual et al., 2007), cervical (Maley et al., 2009), basal cell (Chen et al., 2006) and breast carcinoma (Luker & Luker, 2006). The gene discussed is CXCL12; the disease is breast carcinoma.