CXCL8 and dengue disease: Finally, subgroup analyses of dengue serotypes showed that there are overall significant differences in IL-8, IL-10, and TGF- β levels among different dengue serotypes (p-value of ANOVA <0.05), but no significant differences among individual dengue serotypes when paired comparisons were conducted (p-value of t-test >0.05; see Sheet 8 of  Supplemental Information 2 ).