RANTES, IL-7, and TGF-β are released during platelet activation (De Azeredo, Monteiro & de Oliveira Pinto, 2015; Rathakrishnan et al., 2012; Wasilewska et al., 2005); therefore, a decrease in these biomarkers during SDI could be due to thrombocytopenia, as these biomarkers function to suppress inflammation and viral clearance (Azeredo et al., 2006). This evidence concerns the gene TGFB1 and Thrombocytopenia.