FOXE1 and hematocrit: Evidence such as the Bamforth–Lazarus syndrome [22], or mutations in FOXE1 that explain an association of hypothyroidism and cleft palate [28], in addition to observational and comparative data of human and animal models null for Foxe1 [5, 29] that are consistent with CP, CL, and other thyroid abnormalities, suggests that mutations or SNP in FOXE1 can be a common cause for a possible new syndrome characterized by CL, HT, and PTC.