In this study, mouse hepatoma cells in culture were incubated with a specific kinase inhibitor of CKIε/δ (PF670462, IC50 for CKIε and CKIδ are 7.7 nM and 14 nM, respectively) or DMSO (vehicle) for 48 hours. The gene discussed is CSNK1D; the disease is hepatocellular carcinoma.