Supporting an important role for ILC2s as the source of circulating IL-13, the levels of ILC2-derived IL-13 in response to co-culture with APL cell lines were significantly higher in ILCs from APL patients than controls, while no difference was observed for IFN-γ and IL-17A (Fig. 2b, c). This evidence concerns the gene IFNG and acute promyelocytic leukemia.