FUT2 and ear infection: The high-risk allele rs516316 (C) is in complete LD with rs601338 (A), a nonsense variant in FUT2 that encodes the ‘non-secretor’ (se) allele, which has been reported to provide resistance to Norovirus17 and upper respiratory infections18 (‘non-secretor’ allele is linked to lower rate of childhood ear infections in our GWAS, Supplementary Fig. 5A), and increase risk to Crohn’s disease74 and T1D19.