SPRED2 and psoriasis: We found five risk loci that are also associated with RA (HLA, TNFIP3, CD40, SPRED2 and SH2B3), four loci associated with IBD (HLA, MTMR3, TNFAIP3 and CD40), four loci associated with ulcerative colitis (HLA, GNA12, MAPK3 and NFKB1), three loci associated with psoriasis (HLA, SLC12A8 and 1p36.23), and two loci that are shared with IgAN (HLA and MTMR3).