When comparing HCC and non-HCC cases, profiles of HCC and non-HCC chronic hepatitis B patients were rather different with resistin being the most predictive cytokine followed by IL-7 and IL-8 (AUC = 0.744) and less so for chronic hepatitis C patients (AUC = 0.635). This evidence concerns the gene CXCL8 and hepatocellular carcinoma.