Glutamate receptor expression analysis reveals that the expression of AMPA receptor subunits Gria3 and Gria4 was significantly decreased in FUS tg mice (Fig. S4), consistent with previous studies in which alterations in AMPA receptors contribute to behavioral deficits mimicking FTD (Adamczyk et al., 2012, Gascon et al., 2014, Udagawa et al., 2015). Here, GRIA3 is linked to frontotemporal dementia.