FUS and frontotemporal dementia: Immunohistochemistry and western blot showed that the accumulation of exogenous FUS protein was located prominently in the frontal cortex, hippocampus, and entorhinal cortex, indicating that the accumulation of FUS was restricted to specific cell types (Fig. 1a and b, Fig. S1a), consistent with findings from the brains of patients with FTD (Neumann et al., 2009a, Neumann et al., 2009b).