IL-6 is involved in the proliferation, differentiation and apoptosis resistance of various malignant tumor cells, such as multiple myeloma [110, 111], lung cancer [112], renal cell carcinoma [113, 114], breast cancer [115, 116], colorectal cancer [99, 117], endometrial cancer [118], cervical cancer [119], and ovarian carcinoma [120, 121]. The gene discussed is IL6; the disease is colorectal cancer.