More recently, butyrylcholinesterase (BChE) was identified as a potential imaging target since it also can play a role in acetylcholine metabolism, especially in patients with neurodegenerative diseases such as Alzheimer’s.48 Specific imaging of BChE is a new area of interest, and recently agents specifically targeting BChE have been reported.49,50. The gene discussed is BCHE; the disease is neurodegenerative disease.