We have previously reported that the patients bearing an ovarian cancer highly expressing autophagy‐active Beclin‐1 could experience a better prognosis as compared to those bearing an autophagy‐defective cancer.120 Also, we have shown that ovarian cancer cell migration induced by IL‐6 occurs via downregulation of autophagy.23 Taken together, it is tempting to speculate that poor prognosis in ovarian cancer patients is due to the downregulation of autophagy in cancer cells operated by CAFs, as predicted in the model proposed by Lisanti and colleagues. This evidence concerns the gene BECN1 and cancer.