Based on the co-occurrence of genes and keywords (text mining) in the COREMINE database, eight DEGs (HPX, PGC, ADMTS8, LECT2, NUP210, AP3S2, KLF2 and FABP4) were associated with hypertension, five DEGs (HPX, PGC, ADMTS8, KLF2 and FABP4) were associated with blood pressure, four DEGs (HPX, PGC, KLF2 and FABP4) were associated with oxidative stress, and three DEGs (HPX, PGC and FABP4) were associated with weight gain. The gene discussed is NUP210; the disease is Hypertension.